Using Minoxidil and a Dermaroller Together: Boost Hair Regrowth Results (2025)

• Dr Suhail Alam
• April 15, 2025
• Reading Time: 5 Mins

Looking for ways to tackle hair loss? You’ve likely encountered both dermarolling and minoxidil in your research. While each works well independently, combining them might offer even better results.

Research suggests this combination could be your ticket to fuller hair. But how exactly does it work?

Key Takeaways

• Combined treatment (weekly dermarolling with twice-daily minoxidil) leads to dramatically better results than minoxidil alone, with studies showing 82% of combination users experiencing greater than 50% improvement.
• Wait 24 hours after dermarolling before applying minoxidil to reduce irritation. For at-home use, a 0.5mm needle size provides the best balance of effectiveness and safety.
• Results take time. Expect to wait 2-4 months before seeing noticeable improvements, with the most significant changes typically occurring between months 3-6 of consistent treatment.

Table of Contents

What is Dermarolling?

A dermaroller is a handheld device featuring a roller head studded with hundreds of tiny needles. These needles typically range from 0.25mm to 1.5mm in length.

When rolled across the scalp, the device creates microscopic punctures. Don’t worry about pain. These needles are much smaller than those used for injections.

These micro-injuries trigger your body’s natural healing response. This process is thought to stimulate collagen production and increase blood flow to hair follicles. Thus, activating stem cells in the hair follicle region and potentially enhancing the delivery of topical treatments

A 2015 study found that men with pattern baldness who had previously seen no results from conventional treatments showed significant improvement after 15 microneedling sessions over six months.

What is Minoxidil?

Minoxidil is an FDA-approved treatment for hair loss available over the counter. You can find it as either a foam or a liquid solution.

Originally developed as a blood pressure medication, researchers noticed increased hair growth as a side effect.

It works by extending your hair’s growth phase and improving blood circulation to your follicles. Most users apply it twice daily to affected areas.

Studies show minoxidil alone can increase hair count by 8-14 hairs per square centimetre compared to placebo treatments.

Do Dermaroller and Minoxidil Work Together?

Yes, dermaroller and minoxidil do work together.

Dermarolling creates tiny channels in your scalp that may enhance minoxidil absorption. Meanwhile, each treatment stimulates hair growth through different but complementary mechanisms.

A 2013 study published in the International Journal of Trichology compared results between two groups:

• Group 1: Used 5% minoxidil twice daily
• Group 2: Used 5% minoxidil twice daily plus weekly microneedling

After 12 weeks, the combination group showed a mean hair count increase of 91.4 compared to only 22.2 in the minoxidil-only group.

Even more impressive, 82% of participants in the combination group reported more than 50% improvement, versus just 4.5% in the minoxidil-only group.

A separate 2018 study with 68 men found similar results. The combination group experienced significantly greater hair count increases than those using minoxidil alone.

How to Choose Your Dermaroller

Selecting the right dermaroller is crucial for safety and effectiveness.

For at-home use, stick with needle lengths between 0.25mm and 0.5mm. Professional treatments typically use 1.5mm needles, which penetrate deeper but require trained oversight.

Beginners should start with 0.25mm needles, which cause less discomfort while still providing benefits. As you become more comfortable, you might consider moving up to 0.5mm for potentially better results.

Quality matters too. A good dermaroller typically costs between £15-£30 and should be replaced every 2-3 months.

How to Use a Derma Roller with Minoxidil

Consistency and technique are key to seeing results. Here’s how to safely combine these treatments:

If choosing the DIY route, follow these steps:

1. Clean your scalp thoroughly.
2. Disinfect your dermaroller with 70% isopropyl alcohol for at least 10 minutes.
3. Section your hair to access affected areas.
4. Roll vertically over each section 6 times, then horizontally 6 times.
5. Apply gentle pressure. Your skin may turn pink but shouldn’t bleed.
6. Rinse your scalp with warm water after dermarolling.
7. Clean your dermaroller again with alcohol and store it properly.

However, at-home derma rolling carries significant risks that should be carefully considered. Improper technique can lead to scalp damage through incorrect needle length or excessive pressure, potentially causing redness, inflammation, and even permanent scarring.

Inadequate sterilization presents another serious concern, as bacteria transferred to your scalp may trigger inflammation or infection.

At Aventus Clinic, specialists work with clients at every stage of their hair regrowth journey. Their experts use medical-grade equipment with proper sterilization protocols and determine the appropriate needle length for individual conditions.

A free hair loss online consultation with Aventus specialists provides personalized advice as the first step toward safe, effective hair regeneration.

When to Apply Minoxidil

This is where opinions vary. Some experts recommend waiting 24 hours after dermarolling before applying minoxidil to reduce irritation and absorption of alcohol (found in liquid minoxidil).

Others suggest a minimum waiting period of 30 minutes to allow micro-channels to begin closing.

The 2013 study that showed impressive results had participants apply minoxidil 24 hours after dermarolling, suggesting this approach is both safe and effective.

Most research supports:

• Dermarolling: Once per week
• Minoxidil: Twice daily (morning and evening)

Don’t dermaroll more frequently than recommended. Overuse can irritate your scalp and potentially cause scarring.

What Results Can You Expect?

Patience is essential. Most people begin seeing initial results after 2-4 months of consistent treatment.

The 2013 study showed significant improvements by 12 weeks, with continued gains at 24 weeks. This suggests the benefits are progressive with consistent application.

According to research, you might expect:

• Reduced hair shedding within 8-12 weeks
• Noticeable new growth by 12-16 weeks
• Significant improvement in density by 24 weeks

Taking weekly photos can help you track subtle changes that might otherwise go unnoticed.

Potential Side Effects of Dermarolling with Minoxidil

Both treatments can cause side effects, particularly when used improperly.

Dermarolling may cause:

• Temporary redness and sensitivity
• Mild swelling
• Increased risk of infection if not properly sterilised

Minoxidil commonly causes:

• Scalp irritation or itching
• Dry scalp
• Unwanted hair growth elsewhere if the product migrates

Stop treatment and consult a healthcare provider if you experience persistent irritation, pain, bleeding, or signs of infection.

Alternatives to Microneedling and Minoxidil

If the dermaroller-minoxidil combination isn’t suitable for you, other options exist:

Finasteride blocks dihydrotestosterone (DHT), the hormone primarily responsible for male pattern baldness. A 2019 meta-analysis found that combining oral finasteride with minoxidil yielded better results than either treatment alone.

Platelet-rich plasma (PRP) therapy involves injecting concentrated platelets from your blood into the scalp. A 2019 study combining PRP, microneedling, and minoxidil found 92% of participants achieved moderate to excellent improvement.

Hair transplant surgery offers a permanent solution for appropriate candidates, though at a higher cost.

Low-level laser therapy devices can improve hair growth with regular use and zero discomfort.

Final Thoughts

Scientific evidence strongly suggests that combining dermarolling with minoxidil can significantly enhance hair regrowth compared to using either treatment alone.

Multiple studies show impressive statistical improvements in hair count and patient satisfaction when these treatments are used together.

Before starting any treatment regimen, consult with a hair specialist, particularly if you have underlying skin conditions or take medications that might interact with these treatments.

With patience, consistency, and proper technique, this combination approach offers promising results for many people struggling with hair loss.